Each Gluconormet (1 mg/ 500 mg) contains glimepiride 1 mg and metformin hydrochloride 500 mg.
Each Gluconormet (2 mg/ 500 mg) contains glimepiride 2 mg and metformin hydrochloride 500 mg.
Gluconormet is an oral antidiabetic agent (glimepiride & metformin HCl) used in the management of type 2 diabetes.
Glimepiride: Glimepiride (sulphonylurea class), mechanism of action appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells.
Metformin HCl: Metformin improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose.
Gluconormet is indicated in the treatment of patients with type 2 diabetes mellitus when diet, exercise and single agent do not result in adequate glycemic control.
Gluconormet should be given once daily with full meal preferably in the evening. Therapy should be started with Gluconormet (glimepiride 1 mg & metformin 500 mg) one tablet daily. Depending upon the glycemic control, dose may be titrated to 2 tablets once daily. Alternatively, the therapy may be started with Gluconormet (glimepiride 2 mg & metformin hydrochloride 500 mg) one tablet daily. Depending upon the glycemic control, dose may be titrated to 2 tablets once daily. The maximum daily dose of glimepiride is 8 mg and of metformin is 2000 mg.
Gluconormet (1 mg/500 mg) tablet is available in pack of 30’s. Gluconormet (2 mg/500 mg) tablet is available in pack of 30’s.