Calfina Plus (Tramadol hydrochloride/Acetaminophen) tablets contains tramadol 37.5 mg and acetaminophen 325 mg.
Calfina Plus contains Tramadol hydrochloride & Acetaminophen. Tramadol is a centrally acting synthetic opioid analgesic. The analgesic profile of tramadol is attributed to the binding of parent and M1 metabolite to μ-opioid receptors and weak inhibition of reuptake of norepinephrine and serotonin. Acetaminophen is a non-opiate, non-salicylate analgesic. Acetaminophen also has centrally acting analgesic effects.
Calfina Plus is indicated for management of:
Pain of acute pharyngitis, acute tonsillitis, acute otitis media
Painful diabetic peripheral neuropathy
Calfina Plus can be used in adults and children over 16 years of age for the management of acute pain, the recommended dose of Calfina Plus is 2 tablets every 4 to 6 hours as needed for pain relief, up to a maximum of 8 tablets per day.